Pineapple Lectin AcmJRL Binds SARS-CoV-2 Spike Protein in a Carbohydrate-Dependent Fashion
The corona virus mainly attacks the lungs and airways, and while many recover, it can be dangerous for older people or those with weak immune systems.
Some antiviral drugs like Remdesivir and Paxlovid have been developed to fight the virus but some people experience rebound infections and new medications are still needed.
The virus uses a surface protein popularly known as the spike protein to enter human cells by attaching to a receptor called ACE2. This spike protein is covered in sugars called oligomannose. These sugar coatings help the virus evade the immune system and stick to human cells.
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